La Casa de Doña Ana stands as a neoclassical ancestral home constructed and owned by Pedro Nepomuceno and Ana Maria Herrera-Nepomuceno, who built it several years after their marriage in 1846. This distinguished house represents the sole example of neoclassical architecture found in Lucban and served as a cherished retreat for esteemed visitors hailing from Manila and neighboring towns within Quezon Province. In 1946, Marcelo Dealo and Eduviges Veloso acquired the property, which was later renovated and reestablished as La Dona Ana in 1994 by their descendants, Antonio and Milada Dealo-Valde.